案例：男，50岁。反复发热、乏力1个月。Hb100g/L，WBC3.0×109/L，PLT80×109/L。若该患者ESR70mm/1h末，外周血涂片示红细胞呈缗钱状排列，可见有核红细胞。最可能的病因是

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