To sleep. Perchance to file? Findings published online this week by the Proceedings of the National Academy of Sciences further support the theory that the brain organizes and stows memories formed during the day while the rest of the body is catching zzz's.
Gyorgy Buzsaki of Rutgers University5 and his colleagues analyzed the brain waves of sleeping rats and mice. Specifically, they examined the electrical activity emanating from6 the somatosensory neocortex (an area that processes sensory information) and the hippocampus, which is a center for learning and memory. The scientists found that oscillations in brain waves from the two regions appear to be intertwined. So-called sleep spindles (bursts of activity from the neocortex) were followed tens of milliseconds later by beats in the hippocampus known as ripples. The team posits that this interplay between the two brain regions is a key step in memory consolidation. A second study, also published online this week by the Proceedings of the National Academy of Sciences, links age-associated memory decline to high glucose levels.
Previous research had shown that individuals with diabetes suffer from increased memory problems. In the new work, Antonio Convit of New York University School of Medicine and his collaborators studied 30 people whose average age was 69 to investigate whether sugar levels, which tend to increase with age, affect memory in healthy people as well. The scientists administered11 recall tests, brain scans and glucose tolerance tests, which measure how quickly sugar is absorbed from the blood by the body's tissues. Subjects with the poorest memory recollection, the team discovered, also displayed the poorest glucose tolerance. In addition, their brain scans showed more hippocampus shrinkage than those of subjects better able to absorb blood sugar.
"Our study suggests that this impairment12 may contribute to the memory deficits13 that occur as people age." Convit says. "And it raises the intriguing possibility that improving glucose tolerance could reverse some age-associated problems in cognition.14" Exercise and weight control can help keep glucose levels in check15, so there may be one more reason to go to the gym.
词汇：
perchance adv. 偶然;可能
online n. 在线的
stow vt. 贮藏，堆装
emanate vi. 发源
somatosensory adj. 体觉的
neocortex n. 新(大脑)皮质
oscillation n. 振荡
intertwine v. 缠绕
spindle n. 纺锤体
ripple n. 波动，脉动
diabetes n. 糖尿病
recollection n. 回忆
shrinkage n. 收缩
impairment n. 损伤
intrigue n. 引起。。。兴趣(或好奇心)
cognition n. 认识
注释：
1. file memories：归档并储存记忆。 file：意为 "to put or keep (papers,etc. ) in useful order for storage or reference"(把…归档)。
2. To sleep. Perchance to file? ：从莎士比亚笔下哈姆雷特的独白中的名句" To sleep: perchance to dream. "改编而来。
3. the Proceedings: (科学文献、会议文献)汇编，常用复数形式。
4. zzz：(拟声词)打鼾声
5. Rutgers University：美国新泽西州立大学 (the State University of New Jersey)。
6. emanating from：发源于。
7. neocortex：新(大脑)皮质，尤指大的高等哺乳动物大脑中新生长的部分，也叫做 neopallium。neo-：前縀，意思是"新的"。
8. thehippocampus：大脑侧面脑室壁上的隆起物，也称"海马状突起"，在泛记过程中起主要作用。
9. tens of milliseconds：几十毫秒
10. age-associated memory decline：与年龄相关的记忆衰退
11. administer：实施
12. this impairment：指上句中 hippocampus shrinkage.
13. memory deficits：记忆衰退
14. … the intriguing possibility that improving glucose tolerance could reverse some age-associated problems in cognition：令人兴奋的可能性，即不断改善葡萄糖容许量可以完全改变对某些与年龄相关的认知问题。
15. keep glucose levels in check：限制葡萄糖水平。 in check：在控制中，被阻止。
练习：
1. Which of the following statements is nearest in meaning to the sentence "To sleep. Perchance to file?"? A Does brain arrange memories in useful order during sleep?
B Does brain have memories when one is sleeping?
C Does brain remember files after one falls asleep?
D Does brain work on files in sleep?
2. What is the result of the experiment with rats and mice carried out at Rutgers University?
A The electrical activity is emanating from the somatosensory neocortex.
B Oscillations in brain waves are from hippocampus.
C Somatosensory neocortex and hippocampus work together in memory consolidation.
D Somatosensory neocortex plays it primary role in memory consolidation.
3. What is the relation of memory to glucose tolerance, as is indicated by a research mentioned in paragraph 4?
A People with poor memory have high glucose tolerance.
B People with good memory have low glucose tolerance.
C Memory level has nothing to do with glucose tolerance.
D The poorer the memory, the poorer glucose tolerance.
4. In what way is memory related to hippocampus shrinkage?
A There is no relation between memory and hippocampus shrinkage.
B The more hippocampus shrinks, the poorer one's memory.
C The more hippocampus shrinks, the better one's memory.
D The less hippocampus shrinks, the poorer one's memory.
5. According to the last paragraph, what is the ultimate reason for going to the gym?
A To prevent hippocampus shrinkage.
B To control weight.
C To exercise.
D To control glucose levels.
答案与解释：
1. A文章第一段告诉我们，科学新发现进一步支持了一种理论，即，当人体进入睡眠状态时，大脑对在白天形成的记忆进行组织和储存。 To sleep. Perchance to file?见注释 1和注释 2。
2. C 第二段告诉我们，科学家分析了老鼠的脑电波，尤其是从 somatosensory neocortex和 hippocampus两个区域发出的脑电波。该段是后两句指出，这两个大脑区域的活动是互相作用的。第二段并没有说 somatosensory neocortex或 hippocampus起主导作用。
3. D 该段倒数第二句提供了答案。
4. B 第四段的后一句中 their brain scans，指上句中的 subjects
5. D 锻炼身体和体重控制能保持葡萄糖水平，闲此，去健身房就有了另外一个理由。
译文：
睡眠促使记忆归档存储
睡觉。说不定就是在整理归类记忆?刊登在最近网上出版的国家科学院文献汇编上的新发现进一步证明了这个理论：当人体的其他部分在鼾声中安眠时，人体的大脑就在整理和储存着白天形成的记忆。
美国新泽西州立大学的乔治·Buzsaki和他的同事们分析了睡眠中的老鼠和田鼠的脑波。他们特别研究了源于学习记忆中心——大脑知觉新皮质(充满知觉信息的区域)和大脑侧面脑室壁上的隆起物——的电流活动。科学家们发现，这两个区域的脑波变化仿佛处于交织状态。而10毫秒后大脑侧面脑室壁上的隆起物发出的波动将紧跟着所谓的睡眠纺缍体(新皮质上的种种活动)。这队科学家们假设这两个大脑区域的互动是理解增强记忆的关键。
接下来的研究，同样也是刊登在这周网上出版的国家科学院文献汇编中，是关于与年龄相关的由于葡萄糖浓度过高引起的记忆衰退。
之前的一项研究表明，患糖尿病的人一直受到记忆衰退的困扰。纽约大学医学院的安东尼·康威特及其同事在一项新的工程中研究了30个平均年龄69岁的人，以调查是否血糖浓度，随着年龄增长而增长，同样会影响健康人的记忆。科学家们实施了回忆测试、脑部扫描和血糖浓度容许量测试，以便测量出人体组织从血液中吸收糖分的速度。这对科学家发现，与最次的记忆相对的，是最低的血糖浓度容许量。此外，他们的脑部扫描也显示出海马状突起的缩小要比那些更容易从血液中吸收糖分的人明显。
“我们的研究表明，这种海马状突起的缩小对人类年龄增大而出现的记忆衰退有着不可忽视的影响”，康威特指出，“这一发现大大激增了令人兴奋的可能性，即，不断改善葡萄糖容许量可以完全改变对某些与年龄相关的认知问题。”身体锻炼和体重控制能限制葡萄糖浓度，由此，我们有了更多去健身房的理由。
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