案例：患者男性，19岁，黏液脓血便伴腹痛2个月，入院时腹泻每日6次以上，有明显黏液血便，T大于37.7℃，P大于90次/分，ESR大于30mm/h。该患者经治疗后发现腹痛加剧，腹部立位平片表现为巨大肠腔扭曲，考虑

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• 1案例：患者男性，19岁，黏液脓血便伴腹痛2个月，入院时腹泻每日6次以上，有明显黏液血便，T大于37.7℃，P大于90次/分，ESR大于30mm/h。该患者排除小肠病变、结核及肝炎后，使用何种治疗较为合理

  A.5-ASA和AZA治疗

  B.5-ASA和激素冲击治疗

  C.MTX和使用TNF-α单抗

  D.益生菌和抗生素联合治疗

  E.甲硝唑联合他克莫司治疗

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• 2案例：患者男性，19岁，黏液脓血便伴腹痛2个月，入院时腹泻每日6次以上，有明显黏液血便，T大于37.7℃，P大于90次/分，ESR大于30mm/h。入院后该患者肠镜发现全结肠黏膜充血、水肿，溃疡形成，粪常规见大量白细胞，未见虫卵，首先考虑

  A.溃疡性结肠炎

  B.克罗恩病

  C.肠结核

  D.肠易激综合征

  E.肠癌

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• 3案例：患者男性，19岁，黏液脓血便伴腹痛2个月，入院时腹泻每日6次以上，有明显黏液血便，T大于37.7℃，P大于90次/分，ESR大于30mm/h。目前哪项检查不宜使用

  A.粪常规

  B.p-ANCA和ASCA检测

  C.钡剂灌肠

  D.肠镜

  E.腹部平片

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• 4案例：A 30-year-old man has a history of ulcerative colitis for five years.He has now had acute flare over one week，and developed high fever，bloody diarrhea with bowel movements more than 10 per day，as well as abdominal distention，cecum with a diameter of 13cm，and transverse colon diameter of 8cm on X-ray.Which of the following is the best next step

  A.Oral proton pump inhibitor

  B.Oral azathioprine or 6-Mercaptopurine

  C.Antibiotics and prompt surgical consultation

  D.Diuretic therapy

  E.Oral 5-aminosalicylate

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• 5案例：A 30-year-old man has a history of ulcerative colitis for five years.He has now had acute flare over one week，and developed high fever，bloody diarrhea with bowel movements more than 10 per day，as well as abdominal distention，cecum with a diameter of 13cm，and transverse colon diameter of 8cm on X-ray.Which of the following is the most likely diagnosis

  A.Ulcerative colitis with mild attack

  B.Ulcerative colitis with moderate attack

  C.Ulcerative colitis with colonic perforation

  D.Severe (or fulminant) ulcerative colitis with toxic megalon

  E.Ulcerative colitis with colonic obstruction

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