内科学_自身免疫性肝病
题目内容

A 38-year-old women complains of fatigue,loss of appetite,jaundice for past 6 month.Laboratory studies are significant for atotal bilirubin(82μmol/L)with a direct fraction of 35(μmol/L,alanine aminotransferase(ALT)of 232IU/L,aspartate aminotrasferase(AST)of 126IU/L,both HBV and HCV are negative. Serum ANA 1:320 positive,SMA 1:160 positive,AMA-M2 1:160 positive.Abdominal ultrasound type B shows mild hepatomegaly.Which of the following disease is most likely diagnosis

2021-06-22

A.Autoimmune hepatitis(AIH)

B.Drug-induced liver disease

C.Alholic liver disease(ALD)

D.Primary biliary cirrhosis(PBC)

E.AIH/PBC overlap syndrome

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