Which of the following molecular markers is most important fo r the diagnosis and postoperative observation of colon cancer?

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• 1女，45岁，肛门周围经常潮湿不洁，分泌物有恶臭，且肛门经常发生肿痛，查：距肛门2cm处有乳头状隆起，触之有条状物与肛门相连，有压痛，是何种疾病并需采取哪一种治疗措施

  A.肛管癌行Miles手术

  B.血检性外痔行血栓切除术

  C.单纯肛瘘行手术治疗

  D.外痨无须特殊处理

  E.内痔行环切术

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• 2直肠癌的最早期症状是

  A.大便变细

  B.大便习惯改变

  C.便血

  D.脓样便

  E.排便时疼痛

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• 3有关直肠癌，下列哪项是错误的

  A.多诉有黏液、血便

  B.好发于直肠壶腹部

  C.组织学多为腺癌

  D.其转移以部位越高越复杂

  E.可伴有肠梗阻症状

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• 4有关直肠癌，下列哪项正确

  A.硬癌向肠腔突出

  B.较大的肿瘤突出肠腔内，淋巴结转移发生率大

  C.不论肿瘤位于直肠管内何部位，最理想的治疗方法是腹会阴联合根治切除术

  D.直肠癌的淋巴引流，上、中、下三个方向中，向上转移最重要

  E.直肠癌的淋巴引流，上、中、下三个方向中，向下转移最重要

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• 5直肠癌沿肠壁直接蔓延超过肿瘤边缘距离一般是

  A.不超过lcm

  B.很少超过2〜3cm

  C.很少超过4cm

  D.很少超过5cm

  E.很少超过6cm

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• 6Which of the following is the most accurate description of “triad syndrome of analfissure ” ？

  A.Internal hemorrhoids，external hemorrhoids，anal fissure

  B.Analfissure，internal hemorrhoids，sentinelpile

  C.Internal hemorrhoids，external hemorrhoids，sentinel pile

  D.Anal fissure，sentinel pile，anal papilla hypertrophy

  E.External hemorrhoids， sentinel pile，anal fissure

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• 7Location of anal fissure mostly been found in which clock by knee-chest position ：

  A.twelve

  B.three

  C.nine

  D.six

  E.three and six

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• 8Which one is not suitable to diagnose colon cancer ：

  A.proctoscopy

  B.CEA in serum

  C.CT

  D.gastroscopy

  E.occult blood in stool

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• 9For colon cancer， the spreading distance along the colon wall to the margin of cancer is about ：

  A.lcm

  B.2〜3cm

  C.4〜5cm

  D.5〜6cm

  E.大于6cm

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• 10Which of the follow ing statement about imperforate anus is not true

  A.all the newborns with this disorder w ill die of intestinal obstruction soon if they do not undergo surgical correction

  B.decision of surgical procedure fo rpatient with this disorder is m ainly based on the location or level of the atretic end of rectus

  C.an X -ray film with patient in upside down position taken at 12 hours after birth is needed to show the atretic end

  D.the aim of therapy is not only to achieve successful passage of stool， but afunctioning anus

  E.good postoperative outcome may be expected in patient with low -type anal atresia

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