患者，男，25岁。近年夜頭增多， 偶有水肿。I3P 19(yil0mmHg, 血红蛋白60g/L，尿蛋白 (+ )，取红细胞（ 0 ~ 1 ) 个/HP，A 细胞（ 0 ~ 1 ) 个/HP，颗粒管型(1 ~ 2) 个/HP,肌酐清除率降低。应 诊断为

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