患者，女，59岁，有“乙肝”病史30余年，现右胁疼痛加剧，如锥如刺，入夜更甚，甚至痛引肩背，右胁下结块较大，质硬拒按，面色萎黄而暗，倦怠乏力，复胀，食欲不振，大便溏结不调，月经不调，舌质紫暗有瘀点瘀斑，脉弦涅。诊断为

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