患者男，16岁。左小腿上段肿胀疼痛3个月余，夜间痛明显，查体:左胫骨上段肿胀明显，有压痛，可扪及约6c*7cm质硬包块，固定，X线片显示左胫骨上段虫蚀状溶骨性破坏，骨膜反应明显，可见Codman三角，局部软组织受侵、肿胀。最佳治疗方案是

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