患者，男性，54岁，既往体健。因“全身黄染半年，加重1个月”入院。入院前曾在外院行保肝治疗，效果不佳。查体:神志朦胧，全身皮肤及巩膜黄染，未见肝掌、蝴蛛痣，肝脾肋下未触及；血总胆红素385μmol/L，ALT3218U/L，PT76秒，Alb2.lg/L，最适合患者目前治疗的是

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