案例：患者，男性，27岁。水肿、尿少1周。血压150/100mmHg，尿常规:尿蛋白（++++)，红细胞10〜20个/HP，血尿素氮20mmol/L，肌酐410μmol/L，血红蛋白80g/L。下列检查有助于明确诊断的是

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