案例：患者，女性，62岁。因“右上腹痛伴寒战、高热3天”入院，既往有胆结石病史。入院查体：体温39.5℃，血压80/50mmHg，神志淡漠，巩膜黄染，右上腹压痛，未触及包块，肠鸣音正常。该患者的病灶考虑为急性梗阻性化脓性胆管炎，其典型的临床表现是

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