案例：患儿郭某，女，6岁。上幼儿园。其母诉患儿半月来常用手指挠肛门，夜间睡眠不佳，夜惊、磨牙，粪便中见到过白色线头状小虫，会动。查体:患儿消瘦，烦躁，肛周皮肤有红肿和抓痕。用透明胶纸法粘贴肛周后，镜检査见许多蠕形住肠线虫卵。防治本病的中心环节是

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