7个月女婴，腹泻3天，大便水样，10余次/天，半天无尿。体检：呼吸深，前因、眼眶深度凹陷，皮肤弹性极差，有花纹，四肢凉。血钠135mmol/L,血钾3.8mmol/L，BE-20mmol/L。首先应采取的措施

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