男，4岁。长期偏食。近一个月面色渐苍白，自诉全身无力。査体：肝肋下4cm，脾肋下lcm。血常规：Hb70g/L,RBC3.0x1012/L,Ret2.0%,WBC、PLT均正常，MCV74fl,MCH26pg,MCHC30%。考虑为缺铁性贫血。铁剂治疗有效，首先出现什么变化

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