患儿女，15岁。持续高热6天，颜面出现水肿性皮肤损害，伴膝、踝关节肿痛，下肢水肿，有散在瘀点，化验ESR98mm/h，Hb76g/L,网织红细胞0.10(10%),Coombs试验（+)，PLT40x109/L,尿蛋白（+++)，RBC6-8个/HP。本例最可能的诊断是

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