患儿男，3天，足月顺产，生后5小时出现反复抽搐，皮肤轻度黄染，面部较长，眼距宽,耳位低，耳郭有切迹，下颌小。B超检査患儿房间隔缺损。血白细胞8.5xlO9/L,中性粒细胞0.90,淋巴0.10。引起患儿抽搐的原因是

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