患儿，男，7岁，严重创伤后出现发热、黄疸、明显呼吸困难、少尿，全身多处皮肤瘀斑、瘀点及出血点，血压53/38mmHg。血清胆红素112μmol/L,尿素氮35mmol/L。此患儿少尿带来的最严重的并发症是

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