患者，女，50岁。呕吐、腹泻、低热，门诊每天应用庆大霉素320KU，共5天。近日来觉尿量有所减少，每天700-800ml,伴乏力、头晕。实验室检查尿蛋白(+),Hb100g/L,血清钾6.5mmol/L.BuN33.5mmol/L,Scr884μmol/L。该病例最可能的诊断是

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