患者，男，56岁。有稳定型心绞痛疾病，近期出现心绞痛发作较之前频繁、痛感更强，口服硝酸甘油疼痛10余分钟后缓解，1小时前患者再次出现心绞痛，痛感强烈，口服硝酸甘油后疼痛缓解不明显。该患者最可能的诊断是

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