患者，女，70岁。表情淡漠，言语错乱半年余，行为古怪，记忆力、计弊能力明显下降，行走不稳，智能阶梯性减退。MRI显示脑内多发大小不等的长T1、长T2信号，既往1年前有脑梗死。该患者最有可能的诊断是

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