患者，男，56岁。便中带血、少许白色黏液，伴里急后重7个月，血液呈鲜红色。下腹胀痛拒按，矢气胀减。肛门指诊:于左前壁触及质硬包块，固定，轻度压痛，指套带血，色暗红。血常规Hb77g/L。舌红有瘀斑，苔黄，脉弦数。该患者的首选方药是

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