女，23岁。月经增多8个月，2周来牙龈出血，下肢皮肤散在出血点及瘀斑，血红蛋白78g/L， 白细胞5 .0 x 109/L，血小板计数48 x 109/L，临床诊断为特发性血小板减少性紫癫。该患者治疗中出现严重出血，首选治疗是

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