患者，男性，17岁，近10天来食欲不振、恶心、呕吐，伴乏力、尿黄来医院就诊。病前两周曾注射过丙种球蛋白1支。检查：巩膜黄染，肝肋下1.0cm,有轻度触痛，脾肋下未触及。化验：肝功ALT980U/L,AST560U/L,T-Bil116.5μmol/L,anti-HAV-IgM阳性，HBsAg阳性，anti-HBe阳性，anti-HBc阳性。其母亲为HBV携带者。应诊断为

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