患者，男性，45岁，因上吐下泻住某医院，每天静脉途径给庆大霉素24万U,共9天。近5天来无尿，眼结膜水肿，腹水，下肢水肿。实验室检查：BUN42mol/L,血清肌酐1.04mmol/L,血清钾6.8mmol/L。应诊断为

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