男性,35岁。28小时前饱餐后参加剧烈运动时突发腹痛、腹胀伴阵发性绞痛,并有频繁呕吐,无肛门排气病情加重并晕倒。查体: T 35. 6°C , P 126次/分,BP 80/50mmHg,急性病容,四肢发绀,全腹肌紧张,有压痛和反跳痛,肠鸣音消失,腹穿抽出血性液体。该患者所患疾病最主要的病理生理改变是
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