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1患者男性,13岁。上呼吸道感染后2周出现颜面水肿伴肉眼血尿,血压150/95mmHg,内生肌酐清除率下降,拟诊急性肾炎。实验室检查:血红蛋白95g/L,患者贫血的原因可能是( )
A.水钠潴留,血液稀释
B.骨髓抑制
C.红细胞破坏增多
D.失血
E.促红细胞生成素生成减少
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2患者女性,29岁,间歇性颜面及下肢水肿4年。查体:血压150/95mmHg,Hb90g/L,尿蛋白(++),RBC 15〜20个/HP,BUN 8.7mmol/L,Cr148μmol/L。可能的诊断是( )
A.隐匿性肾炎
B.肾病综合征
C.急性肾炎
D.慢性肾炎
E.高血压肾损害
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3A 60-year-old previously healthy man has been feeling tired for the past 15 days. He goes to his physician when he passes dark-colored urine. On physical examination his blood pressure is 155/90mmHg. Laboratory studies show his serum creatinine is 390μmol/L, P-ANCA 1 : 160( + ). A urinalysis reveals pH 6,specific gravity 1.011,4+ blood,2+ protein, no glucose,and no ketones. Which of the following pathologic findings on renal biopsy is most likely to be present in this man( )
A.大于50% glomerular crescents
B.Widened proximal tubules
C.Lymphocytes infiltration
D.Severe interstitial fibrosis
E.IgA deposited in glomerular capillaries
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4A 39-year-old male presents with a long-standing history of hypertension. Investigations show a urea of 9.2mmol/L and a Creatinine of 142μmol/L. Which one of the following would suggest a diagnosis of acute glomerulonephritis( )
A.24 hour urinary protein excretion of 3.1g
B.Unilaterally smaller kidney
C.RBC casts in urinary sediment
D.Dyslipidaemia
E.Shrunken glomeruli on renal biopsy
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5患者男性,18岁。1周来尿少色红,伴眼睑和双下肢水肿,血压150/90mmHg,尿蛋白(++),RBC10〜20个/HP,WBC5〜10个/HP,血红蛋白136g/L,肌酐 95μmol/L。追问病史,3周前有咽痛发热史。该患者最可能的诊断为( )
A.急性肾炎
B.急进性肾炎
C.急性肾盂肾炎
D.肾病综合征
E.慢性肾炎急性发作
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6A 23 year-old female presents at 16 weeks into her first pregnancy with a blood pressure of 144/96mmHg. A 24 hour urine collection reveals a protein excretion of 1.7g/ d. What is the most likely explanation for these findings( )
A.Normal changes of pregnancy
B.Gestational hypertension
C.Essential hypertension
D.Pre-eclampsia
E.Hypertension secondary to chronic glomerulonephritis
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7患者男性,16岁,上呼吸道感染后2周出现眼睑水肿、肉眼血尿。查体:血压145/90mmHg,血补体下降,血肌酐98μmol/L。其发生水肿的主要机制是( )
A.全身毛细血管通透性增高
B.低白蛋白血症
C.抗利尿激素分泌增加
D.肾小球滤过率下降
E.淋巴回流受阻
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8急性肾小球肾炎的实验室检查改变包括( )
A.血清补体C3下降
B.血清抗链球菌溶血素“O”滴度升高
C.早期血沉升高
D.血清抗核抗体滴度升高
E.血肌酐可一过性升高
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9与溶血性链球菌感染有关的疾病有( )
A.风湿热
B.狼疮性肾炎
C.过敏性紫癜
D.亚急性细菌性心内膜炎
E.急性肾小球肾炎
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10在某些情况下,急性肾小球肾炎需肾活检以进一步明确诊断,如( )
A.病情不典型者,如伴肾病综合征
B.无补体C3持续下降
C.少尿1周以上或进行性尿量减少伴肾功能进行性恶化
D.镜下血尿3个月仍持续存在
E.病情1〜2个月未恢复
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