医药学论文：提高铁人三项运动员血睾酮水平的药物效果实验研究

【摘要】 目的 通过双盲对分组对比实验对提高铁人三项运动员血清睾酮的市售补肾口服液（简称营养品A）和生力君口服液（简称营养品B）进行了人体实验研究。方法 采用双盲交叉对比实验设计。实验1组每日给予A，实验2组每日给予营养品B，空白对照组按B的口服方法给予同等剂量的淀粉安慰剂。在实验4周时，实验1组服用安慰剂，对照组服用A，再进行4周实验。结果 营养品A和营养品B对人体运动训练过程中的低血睾酮现象都具有明显的抑制作用，而且在效果方面，营养品B要明显好于营养品A；营养品A和营养品B在实验过程中，血皮质醇都表现了先下降后回升的变化趋势，而且变化明显（P< 0.05）；营养品A可以在运动训练中抑制血色素的降低，对身体机能恢复具有一定积极影响。在效果方面，实验营养品B药效与营养品A一致，但营养品B效果更明显；营养品A和营养品B都能够提高超氧化物歧化酶的浓度，实验1组与实验2组没有组间差异；营养品A能够使体内MDA浓度降低，可以减少运动后自由基对机体的损伤。营养品B则是在实验后2周时，丙二醛明显降低，而后又出现显著回升。结论 营养品A和营养品B都对提高铁人三项运动员血清睾酮有显著作用。

 

【关键词】 铁人三项运动；血睾酮；实验研究

 

Experimental research of nutriments effect to enhance testosterone level in serum for triathlon athletes

 

 

 

【Abstract】 Objective Through the methods of double-blind， physical experimental research has been taken on oral liquid for reinforcing kidney in sale （nutriment A） and ShengLiJun oral liquid （nutriment B） to enhance triathlon's testosterone level in serum.Methods Through the experimental design of double-blind， chiasm and comparison. Group 1 were given A every day， Group 2 were given B every day， the control group were given starch placebo with the same dosage and same oral ways. At the fourth week， group 1 were given placebo， the control group were given A， and the next four weeks experiment was taken sequentially.Results Nutriment A and nutriment B both have obviously inhibited effect to the low testosterone phenomenon in the course of training. Furthermore， nutriment B's effect is better than A markedly. Cortisol in serum occurs the tendency of firstly descent and then elevation for both A and B in the experiment， and the change is very obvious （P< 0.05）. Nutriment A can inhibit hemoglobin's reducing in the training; it has positive effect to body's enginery comeback. In the effect， nutriment B's function is the same as A， and B's function is more obvious. Both A and B can enhance the concentration of superoxide dismutase（SOD）. There is no difference between group 1 and 2. Nutriment A can reduce the concentration of malondialdehyde（MDA）， and can alleviate body's damage from free radical after exercise. For the nutriment B， at the second week of the experiment， MDA's level reduces evidently， and then ascends evidently.Conclusion Nutriment A and B both have obviously effect to enhance testosterone level in serum for triathlon athletes.

 

 

【Key words】 triathlon; testosterone; experimental research

 

铁三运动员身体的消耗巨大，属于典型的力竭型运动，当然，耗尽的不仅仅是三大能量源，而且影响到身体各器官、组织的功能水平，包括体内的激素水平。采用中医方法诊断的结果，运动性低血睾酮类似中医肾阳虚症候，故据中医理论，应用中药补肾壮阳。本研究针对铁人三项有氧极限运动的特点，探索补肾壮阳合成中药对运动员血清睾酮等指标的影响，目的在于通过药物手段干预血睾酮水平的降低，消除训练后的消极影响，进而为提高机体的运动能力做出科学探讨。