医药学论文:慢性前列腺炎患者的尿动力学检查
【关键词】 慢性前列腺炎
摘 要:目的:探讨慢性前列腺炎可能存在的下尿路症状,结合尿动力学检查分析其原因。方法:采用丹迪尿流测定仪对20例慢性前列腺炎患者进行尿流率、充盈性膀胱侧压、压力―流率测定、尿道侧压及肌电图检查。结果:不稳定性膀胱9例(45%),低顺应性膀胱5例(25%),膀胱出口梗阻11例(55%),逼尿肌尿道括约肌协同失调7例(35%),其中不稳定膀胱合并膀胱出口梗阻6例,低顺应性膀胱合并膀胱出口梗阻4例,不稳定膀胱合并逼尿肌尿道外括约肌协同失调2例。结论:慢性前列腺炎患者的下尿路症状与不稳定性膀胱、低顺应性膀胱、膀胱出口梗阻及逼尿肌尿道外括约肌协同失调有关,了解这些相关因素对治疗有重要的指导意义。
关键词: 尿动力学; 慢性前列腺炎
The Urodynamic Study on Patients with Chronic Prostatitis
Abstract: Objective:The aim of the study was to explore the possible symptom of inferior urinary tract in patients with chronic prostatitis urodynamic. Methods:20 patients with chronic prostatitis urodynamic were measured the urine flow rate , engorged bladder lateral pressure, pressure - flow rate , lateral pressure of urinary tract by using the DANDI urodynamic radiomete and underwent electromyogram examination . Result: Unstable bladder in 9 cases(45%), low compliance bladder in 5 cases (25%) , obstruction in the bladder outlet in 11 cases (55%), dyssynergia in detrusor muscle and external urethral sphincter in 7 cases (35%), unstable bladder with obstruction in the bladder outlet in 6 cases, low compliance bladder with obstruction in the bladder outlet in 4 cases , unstable bladder with dyssynergia in detrusor muscle and external urethral sphincter in 2 cases .Conclusion : The symptom of inferior urinary tract in patients with chronic prostatitis urodynamic was related to the unstable bladder, low compliance bladder , obstruction in the bladder outlet and dyssynergia in detrusor muscle and external urethral sphincter ,to know the correlation factors do significant benefit in guiding the clinical treatment.
Key words: Urodynamic; Chronic prostatitis
慢性前列腺炎(Chronic prostatitis CP)是一种常见病,约占泌尿外科门诊病人的25%,目前对其发病机制不很明确,治疗效果不满意,而尿动力学可对其下尿路症状作出客观反映,为患慢性前列腺炎患者治疗提供理论依据。
1 web/bbs/index.htm' target=_blank>资料与方法
1.1 病例选择:选取2003年1月至2004年6月的CP患者20例,年龄20~40岁,平均28.5岁。患者均有不同程度的下腹会阴部酸胀、尿频、尿急、尿道灼热及排尿不畅症状,所有病例均排除有肾、输尿管疾病、前列腺增生及前列腺癌、睾丸及附睾炎等疾病。20例患者的诊断均符合国际健康学会(NIH)慢性前列腺炎诊断标准[1]。
1.2 检测方法:采用丹迪公司的尿动力学分析仪和自制半卧位床,对20例CP患者进行尿流率、充盈性膀胱测压、压力―流率测定、肌电图同步检测、尿道测压。膀胱测压时用生理盐水按50ml/min持续膀胱灌注,尿道测压时生理盐水灌注速度为2ml/min,导管退出速度为2mm/S。检测前患者常规停药一周。
1.3 诊断标准:①最大尿流率(Qmax)以<15ml/S者为可疑下尿路梗阻,②膀胱出口梗阻(BOO)由A―G图诊断分为梗阻区(O区),非梗阻区(N区),及混合区(M区),③不稳定膀胱,在膀胱充盈时出现自发或诱发无抑制的收缩波且压力≥1.47kPa(15cmH2O),④低顺应性膀胱:膀胱空虚静止压≥1.47kPa(15cmH2O),或充盈后压力上升值≥1.47kPa(15cmH2O)或较少的膀胱容量增加伴迅速压力升高,⑤在排尿期尿道外括约肌肌电图不静息或加强为外括约肌功能失调[2]。
2 结果
本组20例病人,膀胱出口梗阻11例(55%),不稳定膀胱9例(45%),低顺应性膀胱5例(25%),逼尿肌尿道外括约肌协同失调7例(35%)。其中,不稳定膀胱合并膀胱出口梗阻6例,低顺应性膀胱合并膀胱出口梗阻4例,不稳定膀胱合并逼尿肌尿道外括约肌协同失调2例。
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