A common characteristic of acute lymphocytic leukemia is-最需题库

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1Chromosome changes in hematologic neoplasms are
A.present in AL but not MPD or MDS
B.nonrandom
C.associated with a poor outcome
D.not usually present
E.associated with a good outcome
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2Auer rods are inclusions found in
A.myelobfasts
B.lymphoblasts
C.erythrocytes
D.prolymphocytes
E.megakaryocytes
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3The FAB classification is used to divide acute leukemias into groups according to
A.immunology
B.clinical presentation
C.cytogenetics
D.morphology
E.molecular phenotype
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4Immunologic phenotyping of the blast cells is important to
A.help determine cell lineage
B.identify the etiology of the leukemia
C.determine if cytogenetic analysis is necessary
D.replace the need to do multiple cytochemical stains
E.replace the morphologic detection
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5The largest cell found in a normal bone marrow aspirate is the
A.osteoblast
B.megakaryocyte
C.myeloblast
D.pronormoblast
E.metagranulocyte
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6A leukemia that shows a profusion of granulocytes at all stages of development，with the majority of cells being myelocytes and segmented neutrophils，is
A.AML
B.CML
C.ALL
D.CLL
E.MDS
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7The most prominent cell line in CML is the
A.erythroid
B.myeloid
C.megakaryocyte
D.fibroblast
E.lymphoid
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8The Philadelphia chromosome is a gene fusion from a translocation of
A.chromosomes 8 and 14
B.chromosomes 9 and 22
C.chromosomes 12 and 17
D.chromosomes 15 and 17
E.chromosomes 11 and 17
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9Molecular analysis by RT-PCR revealed the presence of a BCR/ABL fusion product.Based on this information，what myeloproliferative disorders is present
A.CML
B.PV
C.ET
D.MMM
E.MDS
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10Which of the following is not typical of an MPD at the time of diagnosis
A.hypercellular bone marrow
B.anemia
C.leukoerythroblastosis
D.predominance of blasts in peripheral blood
E.hepatosplenomegaly
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