11个月婴儿，生后曾有青紫、室息，经抢救后无不适。患儿于半岁内曾经智能筛查未发现异常。单纯母乳喂养，母亲长期素食。近2个月来面色浅黄，表情呆滞，智力发育倒退，头及全身轻度震颤。Hb88g/L，红细胞数2.0x10l2/L。最有诊断意义的辅助检查是

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